Hepatoprotectant potential of amla

Amla is used in the Indian system of medicine for the treatment of liver ailments. Emblica officinalis has the potential to suppress carcinogen‐induced response in rat liver.

The research conducted at Amala cancer research center in Kerala, India, has found that an extract of Phyllanthus emblica significantly inhibited hepato‐carcinogenesis induced by N-nitrosodiethylamine (NDEA) in experimental animals.

Fibrosis of the liver is a state of complicated end-stage alteration of structure and function due to different etiologies. There is no established therapy, and the treatment options require long term administration of putative anti‐fibrotic which must be free of side effects.

Emblica officinalis (fruit) extract reduced the severity of hepatic fibrosis induced by carbon tetrachloride (CCl4) and thioacetamide (TAA). Improvement in liver function was observed by measuring the levels of aspartate aminotransaminase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP) and bilirubin in serum.